abstract：BACKGROUND:Appropriate use criteria (AUC) for stress single-photon emission computed tomography (SPECT) are only one step in appropriate use of imaging. Other steps include pretest clinical risk evaluation and optimal management responses. We sought to understand the link between AUC, risk evaluation, management, and o...

journal_title：American heart journal

authors： Aldweib N,Negishi K,Seicean S,Jaber WA,Hachamovitch R,Cerqueira M,Marwick TH

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:New percutaneous coronary intervention (PCI) device technologies are often rapidly adopted into clinical practice, yet few studies have examined the overall impact of these new technologies on patient outcomes in community practice. METHODS:In hopes of determining temporal trends in PCI outcomes, we used da...

journal_title：American heart journal

authors： Rao SV,Hess CN,Dai D,Green CL,Peterson ED,Douglas PS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Many chronic heart failure (CHF) patients have low vitamin D (VitD) and high plasma renin activity (PRA), which are both associated with poor prognosis. Vitamin D may inhibit renin transcription and lower PRA. We investigated whether vitamin D3 (VitD3) supplementation lowers PRA in CHF patients. METHODS AND...

journal_title：American heart journal

authors： Schroten NF,Ruifrok WP,Kleijn L,Dokter MM,Silljé HH,Lambers Heerspink HJ,Bakker SJ,Kema IP,van Gilst WH,van Veldhuisen DJ,Hillege HL,de Boer RA

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The association between C-reactive protein (CRP) and cardiovascular (CV) mortality by gender has not been previously described using a data set that is representative of the US population. METHODS:We used Cox proportional hazards models to explore gender differences in CRP-associated mortality via the Natio...

journal_title：American heart journal

authors： Doran B,Zhu W,Muennig P

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:ST-elevation myocardial infarctions (STEMI) caused by proximal left-anterior descending (LAD) lesions have more myocardium at risk and worse outcomes than those located in other segments. The aim is to compare outcomes of patients with STEMI and proximal-LAD lesions treated with bare-metal stents (BMS) versu...

journal_title：American heart journal

authors： Gomez-Lara J,Brugaletta S,Gomez-Hospital JA,Ferreiro JL,Roura G,Romaguera R,Martin-Yuste V,Masotti M,Iñiguez A,Serra A,Hernandez-Antolin R,Mainar V,Valgimigli M,Tespili M,den Heijer P,Bethencourt A,Vazquez N,Serruys P,

更新日期：2013-07-01 00:00:00

abstract：:Nearly 800,000 of the 1 million patients hospitalized with acute heart failure (AHF) every year are initially treated by emergency physicians. Signs and symptoms are typically most severe at initial presentation, but with timely diagnostic and therapeutic management, rapid improvement can be achieved. As a direct resu...

journal_title：American heart journal

authors： Collins SP,Levy PD,Pang PS,Gheorghiade M

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Aldosterone antagonist therapy is recommended for selected patients with heart failure and reduced ejection fraction. Adherence to therapy in the transition from hospital to home is not well understood. METHODS:We identified patients with heart failure and reduced ejection fraction who were ≥65 years old, e...

journal_title：American heart journal

authors： Curtis LH,Mi X,Qualls LG,Check DK,Hammill BG,Hammill SC,Heidenreich PA,Masoudi FA,Setoguchi S,Hernandez AF,Fonarow GC

更新日期：2013-06-01 00:00:00

abstract：:Saphenous vein graft (SVG) failure is a common finding in patients following coronary artery bypass graft (CABG) surgery. In the literature SVG failure rates have been reported from 25 to over 50% within 10 years. Although common, it remains unclear to what extent SVG failure affects clinical outcome, due to differenc...

journal_title：American heart journal

authors： Harskamp RE,Williams JB,Hill RC,de Winter RJ,Alexander JH,Lopes RD

更新日期：2013-05-01 00:00:00

abstract：AIMS:Paclitaxel-eluting stents (PESs) have been shown to inhibit neointimal hyperplasia after percutaneous coronary intervention. Coroflex Please (B Braun, Melsungen, Germany) is a newly developed PES. We compared the clinical and angiographic efficacy of Coroflex Please with Taxus Liberte (Boston Scientific, Natick, M...

journal_title：American heart journal

authors： Seo JB,Kang SH,Hur SH,Park KW,Youn TJ,Park JS,Yang HM,Lee HY,Kang HJ,Koo BK,Bae JH,Kim SW,Moon KW,Choi JW,Lee SG,Chung WY,Kim SJ,Kim DI,Kim BO,Hyon MS,Park KS,Cha TJ,Yoo CW,Jeon HK,Kim HS

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Automated implantable cardioverter-defibrillators (ICDs) have become standard therapy for patients at high risk for sudden cardiac death. Linked data allow examination of trends in use and long-term survival after ICD implantation in an adult population. METHODS:Linked state-wide person-based data on hospit...

journal_title：American heart journal

authors： Bradshaw PJ,Stobie P,Briffa T,Hobbs MS

更新日期：2013-05-01 00:00:00

abstract：:Patients with acute coronary syndrome (ACS) need to be risk stratified to deliver the most appropriate therapy. The GRACE and TIMI risk scores have penetrated contemporary guidelines with the former most commonly used in clinical practice. However, ACS prediction models need to be re-evaluated in contemporary practice...

journal_title：American heart journal

authors： Bawamia B,Mehran R,Qiu W,Kunadian V

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Female sex independently predicts bleeding risk after percutaneous coronary intervention (PCI). Bivalirudin is safer than abciximab plus heparin in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Thus, a greater benefit of bivalirudin in women would be expected. METHODS:We performed a...

journal_title：American heart journal

authors： Mehilli J,Neumann FJ,Ndrepepa G,King L,Schulz S,Maimer Rodrigues da Cunha F,Jochheim D,Byrne RA,Hausleiter J,Ott I,Massberg S,Kastrati A,Pache J

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:We evaluated an Internet- and telephone-based telemedicine system for reducing blood pressure (BP) in underserved subjects with hypertension. METHODS:A total of 241 patients with systolic BP ≥140 mm Hg were randomized to usual care (C; n = 121) or telemedicine (T; n = 120). The T group reported BP, heart ra...

journal_title：American heart journal

authors： Bove AA,Homko CJ,Santamore WP,Kashem M,Kerper M,Elliott DJ

更新日期：2013-04-01 00:00:00

abstract：:Reductions in mobility and cognitive function linked to accrual of brain microvascular disease related white matter hyperintensities (WMHs) on magnetic resonance imaging can occur in older hypertensive patients in as little as 2 years. We have designed a trial evaluating 2 levels of ambulatory blood pressure (ABP) con...

journal_title：American heart journal

authors： White WB,Marfatia R,Schmidt J,Wakefield DB,Kaplan RF,Bohannon RW,Hall CB,Guttmann CR,Moscufo N,Fellows D,Wolfson L

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Transradial approach (TRA) for cardiac catheterizations and interventions improves clinical outcomes compared with transfemoral access, and its use is increasing worldwide. However, there are limited data on successive use of same artery for repeat procedures. METHODS:Between May 2010 and May 2011, all cons...

journal_title：American heart journal

authors： Abdelaal E,Molin P,Plourde G,Machaalany J,Bataille Y,Brousseau-Provencher C,Montminy S,Larose E,Roy L,Gleeton O,Barbeau G,Nguyen CM,Noël B,Costerousse O,Bertrand OF

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:We used virtual histology-intravascular ultrasound (VH-IVUS) to investigate the characteristics of culprit lesions in acute coronary syndromes (ACS). BACKGROUND:Autopsy studies of patients who died of ACS have shown that culprit atheromatous plaques almost always contain a large lipid-necrotic core covered ...

journal_title：American heart journal

authors： Cascón-Pérez JD,de la Torre-Hernández JM,Ruiz-Abellón MC,Martínez-Pascual M,Mármol-Lozano R,López-Candel J,Cano P,Fernández C,Ramos JL,Villegas M,Picó-Aracil F

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:A common regimen for patients requiring dual-antiplatelet therapy who are at risk for gastrointestinal complications is the synchronous administration of enteric-coated (EC) aspirin, a proton pump inhibitor, and clopidogrel, although proton pump inhibitors have the potential for pharmacodynamic interaction w...

journal_title：American heart journal

authors： Gurbel PA,Bliden KP,Fort JG,Jeong YH,Shuldiner A,Chai S,Gesheff T,Antonino M,Gesheff M,Zhang Y,Tantry US

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Although controversial, reducing low-density lipoprotein cholesterol (LDL-C) to target levels remains a common therapeutic goal after acute myocardial infarction (AMI). We sought to illuminate patient and provider characteristics associated with LDL-C goal nonattainment after AMI. METHODS:In an observationa...

journal_title：American heart journal

authors： Martin SS,Gosch K,Kulkarni KR,Spertus JA,Mathews R,Ho PM,Maddox TM,Newby LK,Alexander KP,Wang TY

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Declines in case fatality post-myocardial infarction (MI) have been observed over the past 3 decades. Few studies report socioeconomic disparities in survival post-MI. METHODS:We assessed 1-year case fatality among 9,116 incident MI patients included in the Atherosclerosis Risk in Communities community surv...

journal_title：American heart journal

authors： Foraker RE,Patel MD,Whitsel EA,Suchindran CM,Heiss G,Rose KM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Current recommendations for antithrombotic therapy after drug-eluting stent (DES) implantation include prolonged dual antiplatelet therapy (DAPT) with aspirin and clopidogrel ≥12 months. However, the impact of such a regimen for all patients receiving any DES system remains unclear based on scientific eviden...

journal_title：American heart journal

authors： Feres F,Costa RA,Bhatt DL,Leon MB,Botelho RV,King SB 3rd,de Paula JE,Mangione JA,Salvadori D Jr,Gusmão MO,Castello H Jr,Nicolela E Jr,Perin MA,Devito FS,Marin-Neto JA,Abizaid A

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:This study assessed the feasibility of a 12-week program of exercise, with and without intramuscular testosterone supplementation, in male patients with chronic heart failure (CHF) and low testosterone status and collected preliminary data for key health outcomes. METHODS:Male patients with CHF (n = 41, age...

journal_title：American heart journal

authors： Stout M,Tew GA,Doll H,Zwierska I,Woodroofe N,Channer KS,Saxton JM

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The effect of age on diagnostic and prognostic performance of high-sensitivity cardiac troponin T (hs-cTnT) has not been addressed adequately, so far. METHODS:High-sensitivity cardiac troponin T was measured serially in patients with acute symptoms presenting to our emergency department. We tested the diagn...

journal_title：American heart journal

authors： Normann J,Mueller M,Biener M,Vafaie M,Katus HA,Giannitsis E

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Elevations of creatine kinase-MB (CK-MB) and cardiac troponin T (cTnT) have an uncertain long-term prognostic value after coronary artery bypass graft (CABG) surgery. We aimed to test the hypothesis that CK-MB and cTnT are predictors of long-term survival after CABG and to assess which of these 2 biomarkers ...

journal_title：American heart journal

authors： Søraas CL,Friis C,Engebretsen KV,Sandvik L,Kjeldsen SE,Tønnessen T

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Single center studies using serial cerebral diffusion-weighted magnetic resonance imaging in patients having cardiac catheterization have suggested that cerebral microembolism might be responsible for silent cerebral infarct (SCI) as high as 15% to 22%. We evaluated in a multicenter trial the incidence of SC...

journal_title：American heart journal

authors： Hamon M,Lipiecki J,Carrié D,Burzotta F,Durel N,Coutance G,Boudou N,Colosimo C,Trani C,Dumonteil N,Morello R,Viader F,Claise B,Hamon M

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The presence of depression after an acute coronary syndrome (ACS) is associated with worse prognosis and lower adherence to risk-reducing behaviors. We reported earlier that an enhanced depression care intervention reduces depression symptoms and major adverse cardiac events. This study evaluates the impact ...

journal_title：American heart journal

authors： Kronish IM,Rieckmann N,Burg MM,Edmondson D,Schwartz JE,Davidson KW

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Diabetes is associated with a high rate of events after acute coronary syndrome and percutaneous coronary intervention despite aspirin treatment. Once daily aspirin might not provide 24-hour stable biological efficacy in patients with diabetes. We compared the biological efficacy of the same daily dose of as...

journal_title：American heart journal

authors： Dillinger JG,Drissa A,Sideris G,Bal dit Sollier C,Voicu S,Manzo Silberman S,Logeart D,Drouet L,Henry P

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The TRANSFER-AMI study demonstrated that early routine percutaneous coronary intervention post-fibrinolysis (pharmacoinvasive strategy) is superior to conservative management for ST-elevation myocardial infarction. However, it is not clear whether treatment efficacy differs between men and women. METHODS:In...

journal_title：American heart journal

authors： Bhan V,Cantor WJ,Yan RT,Mehta SR,Morrison LJ,Heffernan M,Fitchett D,Džavík V,Ducas J,Borgundvaag B,Cohen EA,Goodman SG,Yan AT

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Women with X-chromosome monosomy or Turner syndrome (TS) are at increased risk for aortic dilation and dissection. To better understand the pathology and develop tools to monitor the risk of aortic disease, we investigated N-terminal pro-brain natriuretic peptide (BNP) (NT-proBNP) levels in women with TS and...

journal_title：American heart journal

authors： Gutin LS,Bakalov VK,Rosing DR,Arai AE,Gharib AM,Bondy CA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Current acetylsalicylic acid (ASA) dosing algorithms for the prevention of secondary thrombotic events in acute coronary syndrome (ACS) patients are inconsistent and lack sufficient data support. METHODS:We performed a systematic review of the literature for studies that assessed clinical outcomes in patien...

journal_title：American heart journal

authors： Berger JS,Sallum RH,Katona B,Maya J,Ranganathan G,Xu Y,Mwamburi M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Although there is evidence linking smoking and heart failure (HF), the association between lifetime smoking exposure and HF in older adults and the strength of this association among current and past smokers is not well known. METHODS:We examined the association between smoking status, pack-years of exposur...

journal_title：American heart journal

authors： Gopal DM,Kalogeropoulos AP,Georgiopoulou VV,Smith AL,Bauer DC,Newman AB,Kim L,Bibbins-Domingo K,Tindle H,Harris TB,Tang WW,Kritchevsky SB,Butler J

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:We analyzed the antiplatelet effects of different P2Y(12) receptor blockers with VerifyNow P2Y12 assay (VN-P2Y12) and light transmittance aggregometry (LTA). BACKGROUND:The point-of-care VN-P2Y12 has been used to assess the antiplatelet effects in clopidogrel-treated patients but has not been evaluated in d...

journal_title：American heart journal

authors： Jeong YH,Bliden KP,Antonino MJ,Park KS,Tantry US,Gurbel PA

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus and impaired glucose metabolism are associated with increased risk for cardiovascular disease (CVD). However, it is still not clear whether glucose levels can predict CVD risk among patients without diabetes. The primary aim of this study is to assess whether normoglycemic fasting plasma gl...

journal_title：American heart journal

authors： Shaye K,Amir T,Shlomo S,Yechezkel S

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Half of patients with hypertension have poor blood pressure (BP) control. Recent models for treating hypertension have integrated disease monitoring and telephone-based interventions delivered in patients' homes. This study evaluated the costs of the Hypertension Intervention Nurse Telemedicine Study (HINTS)...

journal_title：American heart journal

authors： Wang V,Smith VA,Bosworth HB,Oddone EZ,Olsen MK,McCant F,Powers BJ,Van Houtven CH

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The magnitude of benefit of cardiac resynchronization therapy (CRT) varies significantly among its recipients; approximately 30% of CRT patients do not report clinical improvement. Optimization of CRT pacing parameters can further improve cardiac function, both acutely and chronically. Echocardiographic opti...

journal_title：American heart journal

authors： Krum H,Lemke B,Birnie D,Lee KL,Aonuma K,Starling RC,Gasparini M,Gorcsan J,Rogers T,Sambelashvili A,Kalmes A,Martin D

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Heart failure still maintains a high mortality. Biomarkers reflecting different pathophysiological pathways are under evaluation to better stratify the mortality risk. The objective was to assess high-sensitivity cardiac troponin T (hs-cTnT) in combination with N-terminal pro-B type natriuretic peptide (NT-p...

journal_title：American heart journal

authors： de Antonio M,Lupon J,Galan A,Vila J,Urrutia A,Bayes-Genis A

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The optimal antiplatelet regimen in elective patients undergoing complex percutaneous coronary interventions (PCIs) is uncertain. We aimed to assess the impact of glycoprotein IIb/IIIa (GpIIb/IIIa) inhibition with eptifibatide in clinically stable subjects with diffuse coronary lesions. METHODS:Patients wit...

journal_title：American heart journal

authors： Biondi-Zoccai G,Valgimigli M,Margheri M,Marzocchi A,Lettieri C,Stabile A,Petronio AS,Binetti G,Bolognese L,Bellone P,Sardella G,Contarini M,Sheiban I,Marra S,Piscione F,Romeo F,Colombo A,Sangiorgi G

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Drug-eluting stents (DES) are increasingly used for the treatment of coronary artery disease. An optimized DES performance is desirable to successfully treat various challenging coronary lesions in a broad population of patients. In response to this demand, third-generation DES with an improved deliverabilit...

journal_title：American heart journal

authors： Tandjung K,Basalus MW,Sen H,Jessurun GA,Danse PW,Stoel M,Linssen GC,Derks A,van Loenhout TT,Nienhuis MB,Hautvast RW,von Birgelen C

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Despite lower risks of access site-related complications with transradial approach (TRA), its clinical benefit for percutaneous coronary intervention (PCI) is uncertain. We conducted a systematic review and meta-analysis of clinical studies comparing TRA and transfemoral approach (TFA) for PCI. METHODS:Rand...

journal_title：American heart journal

authors： Bertrand OF,Bélisle P,Joyal D,Costerousse O,Rao SV,Jolly SS,Meerkin D,Joseph L

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:We aimed to study the comparative safety and effectiveness of various antithrombotic treatment strategies among older adults with non-ST elevation myocardial infarction (NSTEMI) and atrial fibrillation (AF). METHODS:Using the CRUSADE registry linked to longitudinal Medicare claims data, we examined NSTEMI p...

journal_title：American heart journal

authors： Fosbol EL,Wang TY,Li S,Piccini JP,Lopes RD,Shah B,Mills RM,Klaskala W,Alexander KP,Thomas L,Roe MT,Peterson ED

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Experimental studies suggest that metabolic myocardial support by intravenous (IV) glucose, insulin, and potassium (GIK) reduces ischemia-induced arrhythmias, cardiac arrest, mortality, progression from unstable angina pectoris to acute myocardial infarction (AMI), and myocardial infarction size. However, tr...

journal_title：American heart journal

authors： Selker HP,Beshansky JR,Griffith JL,D'Agostino RB,Massaro JM,Udelson JE,Rashba EJ,Ruthazer R,Sheehan PR,Desvigne-Nickens P,Rosenberg YD,Atkins JM,Sayah AJ,Aufderheide TP,Rackley CE,Opie LH,Lambrew CT,Cobb LA,Macleod BA

更新日期：2012-03-01 00:00:00